Is it possible to paint an overly bleak picture of university based clinical research?

December 13, 2017
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(This article was originally published at Statistical Modeling, Causal Inference, and Social Science, and syndicated at StatsBlogs.)

Recently I was reminiscing with an old colleague about  how our publications from almost 30 years ago that tried to encourage better conduct and reporting of clinical research seemed to have had so little impact. This one for instance.

Recently, they suggested there is some reason to hope for better, pointing to a website reporting on failures to enable open science by failure to share trial results.  If reason has little impact maybe some wider public awareness might work? So I checked the data on the list from the link they gave for some of the universities I was associated with in the past – [edit – sorted by percent missing] they were at the 11th, 32nd, 49th and 72nd percentile (higher being better). I was hoping they would in the 80th or higher.  Perhaps surprisingly, the higher percentiles seem to be occupied mostly by pharma for profit companies.

Then by distraction I happened across this. They focus on pharma for profit companies’ sharing of their trial results in a particular setting. It’s complicated, but better and improving.

I am sure there are some good reasons for the deficiencies being reported in universities (e.g. lack of resources, career pressures, inappropriate incentives, etc.) but this does need to change. Will  wider public awareness work in a university setting?

The post Is it possible to paint an overly bleak picture of university based clinical research? appeared first on Statistical Modeling, Causal Inference, and Social Science.



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