Posts Tagged ‘ experimental design ’

Mathematics and Applied Statistics Lesson of the Day – Contrasts

Mathematics and Applied Statistics Lesson of the Day – Contrasts

A contrast is a linear combination of a set of variables such that the sum of the coefficients is equal to zero.  Notationally, consider a set of variables . Then the linear combination is a contrast if . There is a reason for why I chose to use as the symbol for the variables in […]

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Mathematics and Applied Statistics Lesson of the Day – Contrasts

Mathematics and Applied Statistics Lesson of the Day – Contrasts

A contrast is a linear combination of a set of variables such that the sum of the coefficients is equal to zero.  Notationally, consider a set of variables . Then the linear combination is a contrast if . There is a reason for why I chose to use as the symbol for the variables in […]

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Applied Statistics Lesson of the Day – Notation for Fractional Factorial Designs

Applied Statistics Lesson of the Day – Notation for Fractional Factorial Designs

Fractional factorial designs use the notation; unfortunately, this notation is not clearly explained in most textbooks or web sites about experimental design.  I hope that my explanation below is useful. is the number of levels in each factor; note that the notation assumes that all factors have the same number of levels. If a factor has […]

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Applied Statistics Lesson of the Day – Fractional Factorial Design and the Sparsity-of-Effects Principle

Applied Statistics Lesson of the Day – Fractional Factorial Design and the Sparsity-of-Effects Principle

Consider again an experiment that seeks to determine the causal relationships between  factors and the response, where .  Ideally, the sample size is large enough for a full factorial design to be used.  However, if the sample size is small and the number of possible treatments is large, then a fractional factorial design can be used instead.  Such a […]

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Applied Statistics Lesson of the Day – The Independent 2-Sample t-Test with Unequal Variances (Welch’s t-Test)

Applied Statistics Lesson of the Day – The Independent 2-Sample t-Test with Unequal Variances (Welch’s t-Test)

A common problem in statistics is determining whether or not the means of 2 populations are equal.  The independent 2-sample t-test is a popular parametric method to answer this question.  (In an earlier Statistics Lesson of the Day, I discussed how data collected from a completely randomized design with 1 binary factor can be analyzed […]

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Applied Statistics Lesson of the Day – Additive Models vs. Interaction Models in 2-Factor Experimental Designs

Applied Statistics Lesson of the Day – Additive Models vs. Interaction Models in 2-Factor Experimental Designs

In a recent “Machine Learning Lesson of the Day“, I discussed the difference between a supervised learning model in machine learning and a regression model in statistics.  In that lesson, I mentioned that a statistical regression model usually consists of a systematic component and a random component.  Today’s lesson strictly concerns the systematic component. An […]

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Applied Statistics Lesson of the Day – The Full Factorial Design

Applied Statistics Lesson of the Day – The Full Factorial Design

An experimenter may seek to determine the causal relationships between factors and the response, where .  On first instinct, you may be tempted to conduct separate experiments, each using the completely randomized design with 1 factor.  Often, however, it is possible to conduct 1 experiment with  factors at the same time.  This is better than […]

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Applied Statistics Lesson of the Day – The Matched-Pair (or Paired) t-Test

Applied Statistics Lesson of the Day – The Matched-Pair (or Paired) t-Test

My last lesson introduced the matched pairs experimental design, which is a special type of the randomized blocked design.  Let’s now talk about how to analyze the data from such a design. Since the experimental units are organized in pairs, the units between pairs (blocks) are not independently assigned.  (The units within each pair are […]

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Applied Statistics Lesson of the Day – The Matched Pairs Experimental Design

Applied Statistics Lesson of the Day – The Matched Pairs Experimental Design

The matched pairs design is a special type of the randomized blocked design in experimental design.  It has only 2 treatment levels (i.e. there is 1 factor, and this factor is binary), and a blocking variable divides the experimental units into pairs.  Within each pair (i.e. each block), the experimental units are randomly assigned to the […]

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Applied Statistics Lesson of the Day – Blocking and the Randomized Complete Blocked Design (RCBD)

Applied Statistics Lesson of the Day – Blocking and the Randomized Complete Blocked Design (RCBD)

A completely randomized design works well for a homogeneous population - one that does not have major differences between any sub-populations.  However, what if a population is heterogeneous? Consider an example that commonly occurs in medical studies.  An experiment seeks to determine the effectiveness of a drug on curing a disease, and 100 patients are recruited […]

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