Blog Archives

Which countries have Regrexit?

June 26, 2016
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Which countries have Regrexit?

This doesn't have a lot to do with bio part of biostatistics, but is an interesting data analysis that I just started. In the wake of the Brexit vote, there is a petition for a redo. The data for the petition is here, in JSON format.Fortunately, in R, ...

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Little Debate: defining baseline

June 5, 2016
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Little Debate: defining baseline

In an April 30, 2015 note in Nature (vol 520, p. 612), Jeffrey Leek and Roger Peng note that p-values get intense scrutiny, while all the decisions that lead up to the p-values get little debate. I wholeheartedly agree, and so I'm creating a Littl...

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Simulating a Weibull conditional on time-to-event is greater than a given time

May 20, 2016
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Simulating a Weibull conditional on time-to-event is greater than a given time

Recently, I had to simulate a time-to-event of subjects who have been on a study, are still ongoing at the time of a data cut, but who are still at risk of an event (e.g. progressive disease, cardiac event, death). This requires the simulation of a con...

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The American Statistical Association makes a statement on p-values

March 8, 2016
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The American Statistical Association makes a statement on p-values

This deserves to be read, re-read, re-re-read, and taken to heart. The ASA makes their statement on p-values.Some key points:p-values by themselves offer very little information on the utility of a model, the truth of a statement, or what is behind a d...

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Talk to Upstate Data Science Group on Caret

January 14, 2016
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Talk to Upstate Data Science Group on Caret

Last night I gave an introduction and demo of the caret R package to the Upstate Data Science group, meeting at Furman University. It was fairly well attended (around 20 people), and well received.It was great to get out of my own comfort zone a b...

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Even the tiniest error messages can indicate an invalid statistical analysis

November 25, 2015
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Even the tiniest error messages can indicate an invalid statistical analysis

The other day, I was reading in a data set in R, and the function indicated that there was a warning about a parsing error on one line. I went ahead with the analysis anyway, but that small parsing error kept bothering me. I thought it was just one lin...

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Statisticians ruin the day again, this time with a retraction

October 22, 2015
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Statisticians ruin the day again, this time with a retraction

Authors retract second study about medical uses of honey - Retraction Watch at Retraction Watch: For the second time, authors of manuscripts have had to retract their papers because of serious data analysis errors. While the details of the actual error...

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The thirty-day trial

October 15, 2015
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The thirty-day trial

Steve Pavlina wrote about a self-help technique called the thirty-day trial. To perform the technique, you commit 30 days of some new habit, such as quitting smoking or writing in a journal. The idea is that it’s psychologically easier to commit to s...

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Statistics: P values are just the tip of the iceberg : Nature News & Comment

May 8, 2015
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Statistics: P values are just the tip of the iceberg : Nature News & Comment

Statistics: P values are just the tip of the iceberg : Nature News & Comment: This article is very important. Yes, p-values reported in the literature (or in your own research) need scrutiny, but so does every step in the analysis process, starting...

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The many faces of the placebo response

April 17, 2015
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The many faces of the placebo response

This week, a study was published that claimed that the placebo response is mediated by genetics. Though I need to dig a little deeper and figure out exactly what this article is saying, I do think we need to take a step back and remember what can const...

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